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Research ArticleHead & Neck

Imaging Findings of Head and Neck Dermatofibrosarcoma Protuberans

G.G. Millare, N. Guha-Thakurta, E.M. Sturgis, A.K. El-Naggar and J.M. Debnam
American Journal of Neuroradiology February 2014, 35 (2) 373-378; DOI: https://doi.org/10.3174/ajnr.A3650
G.G. Millare
aFrom the Department of Diagnostic Radiology (G.G.M.), Baylor College of Medicine, Houston, Texas
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N. Guha-Thakurta
bDepartment of Diagnostic Radiology (N.G.-T., J.M.D.), Section of Neuroradiology
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E.M. Sturgis
cDepartments of Head and Neck Surgery (E.M.S.)
dEpidemiology (E.M.S.)
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A.K. El-Naggar
ePathology (A.K.E.-N.), The University of Texas MD Anderson Cancer Center, Houston, Texas.
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J.M. Debnam
bDepartment of Diagnostic Radiology (N.G.-T., J.M.D.), Section of Neuroradiology
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Article Figures & Data

Figures

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    Fig 1.

    A 31-year-old woman (patient 10) with DFSP of the right parietal scalp. Contrast-enhanced axial CT in soft tissue (A) and bone window (B) shows a 6.1 × 4.8-cm heterogeneously enhancing mass (A, arrow) that bulges the skin surface outward and thins underlying calvaria (B, arrow).

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    Fig 2.

    A 31-year-old man (patient 1) with DFSP of the parietal midline scalp. MR imaging shows a 3.5 × 1.8-cm T1-isointense, T2-hyperintense, coalescing nodular mass with marked homogeneous enhancement in the parietal midline scalp (arrows). A, Axial noncontrast T1. B, Fast spin-echo T2 with fat saturation. C, T1 postcontrast axial with fat saturation. D, T1 postcontrast coronal with fat saturation.

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    Fig 3.

    Photographs of 2 patients with DFSP. A, Patient 16, a 25-year-old man with a large DFSP of the scalp extending from the midline near the vertex down to the left lower parietal region with subcutaneous infiltration. B, Patient 10, a 31-year-old woman with a large DFSP of the right paramedian posterior parietal scalp.

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    Fig 4.

    Pathologic specimen of DFSP. A, Hematoxylin and eosin stain. Elongated spindle cells with a storiform (whorled) pattern arranged around foci of collagen or vascular spaces, radiating outward (arrows). B, CD34 stain. The specimen is positive for CD34 staining. Fat entrapment is noted with a honeycomb pattern (arrow).

Tables

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  • Patient demographics and image appearance

    PatientAge, Years/SexLocationCT Enhancement PatternMR Appearance (T2)MR T1 Enhancement
    131/MParietal midline scalpNAHyperintenseMarked homogeneous
    268/MRight cheekHomogeneousNANA
    337/MFrontal paramedian scalpHomogeneousNANA
    466/MFrontal midline scalpHeterogeneousHyperintenseMarked homogeneous
    539/FFrontal midline scalpNAHyperintenseMild
    646/FFrontal midline scalpNAHyperintenseMarked homogeneous
    725/FRight parietal paramedian scalpMinimalNANA
    829/FRight pre-auricular regionHomogeneousNANA
    958/FFrontal midline scalpNAHyperintenseMarked homogeneous
    1031/FRight parietal scalp near midlineHeterogeneousHyperintenseMarked heterogeneous
    1145/MLeft parietal paramedian scalpMinimalNANA
    1242/MParietal scalp near midlineNAHyperintenseMarked heterogeneous
    1348/FParietal midline scalpHomogeneousNANA
    1415/FFrontal paramedian scalpNAIso-/hypointenseMarked homogeneous
    1540/MFrontal paramedian scalpHomogeneousNANA
    1625/MParietal scalp to midlineHeterogeneousNANA
    1764/FMidline chinMinimalNANA
    1836/MMidline occipital scalpNAHyperintenseMarked heterogeneous
    1934/MRight frontal scalpNAHypointenseMarked homogeneous
    2072/FRight posterior neckHomogeneousHyperintenseMarked heterogeneous
    2155/MLeft face to midlineNAIso-/hypointenseMarked homogeneous
    2242/MParieto-occipital scalpHomogeneousHypointenseMarked homogeneous
    2331/FParietal scalp to midlineHomogeneousNANA
    2440/FParietal scalpNAHyperintenseMarked homogeneous
    • Note:—NA indicates not applicable.

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American Journal of Neuroradiology: 35 (2)
American Journal of Neuroradiology
Vol. 35, Issue 2
1 Feb 2014
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Cite this article
G.G. Millare, N. Guha-Thakurta, E.M. Sturgis, A.K. El-Naggar, J.M. Debnam
Imaging Findings of Head and Neck Dermatofibrosarcoma Protuberans
American Journal of Neuroradiology Feb 2014, 35 (2) 373-378; DOI: 10.3174/ajnr.A3650

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Imaging Findings of Head and Neck Dermatofibrosarcoma Protuberans
G.G. Millare, N. Guha-Thakurta, E.M. Sturgis, A.K. El-Naggar, J.M. Debnam
American Journal of Neuroradiology Feb 2014, 35 (2) 373-378; DOI: 10.3174/ajnr.A3650
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