Article Figures & Data
Figures
- Fig 1.
Sample of the FTFT-2D input data for texture analysis. A, Original DICOM MR image (T2WI). B, Region-of-interest mask of the tumor.
- Fig 2.
Tumors outlined on source MR images (Post-Gad T1WI) of 256 × 256 image size. The tumor in the left image is p53-negative. The tumor in the right image is p53-positive.
- Fig 3.
Graphic display of the average local spectrum for a p53-negative tumor (left image, black shades) and for a p53-positive tumor (right image, blue shades). The average amplitudes of ST at individual pixels were obtained by using FTFT-2D by using the same intensity range and scale for the 2 plots. Darker shades indicate higher ST amplitudes.
- Fig 4.
Radial ST amplitude plots for a p53-negative (black line) tumor and a p53-positive (blue line) tumor (the same tumor as in Fig 3).
Tables
Characteristic p53-Positive p53-Negative Female 1 1 Male 7 7 Age (yr) (mean) 56 ± 13 56 ± 11 T2 1 3 T3 2 1 T4 5 4 N1 1 1 N2 7 7 ↵a All P values are not significant.
Texture Attribute MRI Sequence Radial Frequency Band (cycles/mm) Average value of the local spectrum ADC map 0.189–0.231 0.269–0.307 0.307–0.344 0.344–0.382 Post-Gad T1WI 0.382–0.420 SD of the local spectrum ADC map 0.307–0.344 0.496–0.533 Post-Gad T1WI 0.420–0.458 0.458–0.496 0.496–0.533 Maximum value of the local spectrum ADC map 0.231–0.269 0.269–0.307 Post-Gad T1WI 0.382–0.420 0.496–0.533 T2WI 0.496–0.533 Note:—SD indicates standard deviation.
TP Rate FP Rate Precision Recall F-Measure ROC Area p53-Positive 0.625 0.375 0.625 0.625 0.625 0.680 p53-Negative 0.625 0.375 0.625 0.625 0.625 0.680 Weighted average 0.625 0.375 0.625 0.625 0.625 0.680 Note:—BN indicates Bayesian network; FP, false-positive; TP, true-positive; ROC, receiver operating characteristic.
Texture Attribute MRI Sequence Radial Frequency Band (cycles/mm) Average value of the local spectrum ADC map 0.269–0.307 SD of the local spectrum Post-Gad T1WI 0.458–0.496 0.496–0.533 Maximum value of the local spectrum ADC map 0.269–0.307 Post-Gad T1WI 0.382–0.420 0.496–0.533 T2WI 0.496–0.533 TP Rate FP Rate Precision Recall F-Measure ROC Area p53 Status p53-Positive 0.875 0.250 0.778 0.875 0.824 0.742 Positive p53-Negative 0.750 0.125 0.857 0.750 0.800 0.742 Negative Weighted average 0.813 0.188 0.817 0.813 0.812 0.742 Note:—BN indicates Bayesian network; FP, false-positive; ROC, receiver operating characteristic; TP, true-positive.
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