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The authors performed a crossover, intraindividual comparison of 0.1-mmol/kg gadobenate with 0.1-mmol/kg gadoterate (Arm 1) and 0.05-mmol/kg gadobenate with 0.1-mmol/kg gadoterate (Arm 2). In Arm 1, a significant superiority of 0.1-mmol/kg gadobenate was demonstrated by all readers for all end points. In Arm 2, no significant differences were observed for any reader and any end point, with the exception of percentage enhancement for reader 2 in favor of 0.05-mmol/kg gadobenate.

Relative CBV estimates were calculated from dynamic susceptibility contrast MR imaging in double-baseline examinations of 33 patients with treatment-naïve and pathologically proved glioblastoma multiforme. Normalized and standardized relative CBV were calculated by using 6 common postprocessing methods. The ΔR2* estimation method that incorporates leakage correction offers the best repeatability for rCBV, with standardized rCBV being less variable.

A group of 111 consecutive patients with untreated oral cavity squamous cell carcinoma and available preoperative imaging and subsequent lymph node dissection was studied. Twenty nine subjects had radiographically determined extracapsular spread. Imaging sensitivity and specificity for extracapsular spread were 68% and 88%, respectively. Necrosis, irregular borders, and gross invasion were independently correlated with pathologically proved extracapsular spread.