Index by author

The purpose of this study was to use a validated brain MRI scoring system (Bern score) to evaluate patients with confirmed skull base CSF leaks for findings associated with SIH. The authors found that patients with skull base CSF leaks did not have brain MRI findings that are associated with SIH and likely have distinct pathophysiology from spinal CSF leaks.

Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.