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Index by author

March 01, 2025; Volume 46,Issue 3

  1. Xia, Erwin E.

    1. EDITOR'S CHOICEArtificial Intelligence
      AI-Generated Synthetic STIR of the Lumbar Spine from T1 and T2 MRI Sequences Trained with Open-Source Algorithms
      Alice M.L. Santilli, Mark A. Fontana, Erwin E. Xia, Zenas Igbinoba, Ek Tsoon Tan, Darryl B. Sneag and J. Levi Chazen
      American Journal of Neuroradiology March 2025, 46 (3) 552-558; DOI: https://doi.org/10.3174/ajnr.A8512

      This proof-of-concept investigation used open-source generative adversarial networks to create synthetic lumbar spine MRI STIR from T1 and T2 sequences. Evaluating radiologists found the synthetic volumes were of equal or better quality in 77% of test patients and demonstrated equivalent or decreased motion artifacts in 78% of test patients. The synthetic volumes had high positive predictive value (75%-100%) but lower sensitivity (0%-67%) for common pathologies. The results from this study are a promising first step toward expediting imaging protocols.

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