More articles from ADULT BRAIN
- Utility and Significance of Gadolinium-Based Contrast Enhancement in Posterior Reversible Encephalopathy Syndrome
The authors report on a cohort of 135 patients with clinically confirmed PRES who received gadolinium-based contrast and evaluate symptoms, etiology, and clinical follow-up. The most common pattern seen was leptomeningeal (17.8*) or leptomeningeal plus cortical (15.6*). No association was found between the presence or pattern of enhancement and any of the variables, which included sex, age, symptoms, blood pressure, and outcome.
- MR Elastography Demonstrates Increased Brain Stiffness in Normal Pressure Hydrocephalus
The authors performed MR elastography on 10 patients with normal pressure hydrocephalus and 21 age- and sex-matched volunteers. Shear waves with 60-Hz vibration frequency were transmitted to the brain by a pillow-like passive driver. Significant increase in stiffness was observed in the cerebrum, occipital lobe, parietal lobe, and temporal lobe in the NPH group compared with controls.
- Disorders of Microtubule Function in Neurons: Imaging Correlates
MRIs from 18 patients with confirmed tubulin mutations and 15 patients with mutations of the genes encoding microtubule-associated proteins were evaluated. The patients with tubulin gene mutations were found to have cortical and subcortical abnormalities such as microcephaly, ventriculomegaly, abnormal gyral and sulcal patterns, small or absent corpus callosum, and a small pons. Fewer subcortical abnormalities were seen in the microtubule-associated protein mutations group.