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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Percutaneous CT-Guided Microwave Ablation Combined with Vertebral Augmentation for Treatment of Painful Spinal Metastases

L. Chen, G. Hou, K. Zhang, Z. Li, S. Yang, Y. Qiu, Q. Yuan, D. Hou and X. Ye
American Journal of Neuroradiology February 2022, DOI: https://doi.org/10.3174/ajnr.A7415
L. Chen
aFrom the Departments of Oncology (L.C., K.Z., S.Y., Y.Q., Q.Y.)
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G. Hou
bCardiology (G.H.)
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K. Zhang
aFrom the Departments of Oncology (L.C., K.Z., S.Y., Y.Q., Q.Y.)
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Z. Li
cOrthopedics (Z.L.), Tengzhou Central People’s Hospital Affiliated with Jining Medical University, Tengzhou, Shandong Province, China
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S. Yang
aFrom the Departments of Oncology (L.C., K.Z., S.Y., Y.Q., Q.Y.)
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Y. Qiu
aFrom the Departments of Oncology (L.C., K.Z., S.Y., Y.Q., Q.Y.)
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Q. Yuan
aFrom the Departments of Oncology (L.C., K.Z., S.Y., Y.Q., Q.Y.)
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D. Hou
dDepartment of Radiation Oncology (D.H.), Beijing Shijitan Hospital Affiliated with Capital Medical University, Haidian District, Beijing, China
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X. Ye
eDepartment of Minimally Invasive Oncology (X.Y.), Shandong Provincial Qianfoshan Hospital, Jinan, Shandong Province, China
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  • FIG 1.
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    FIG 1.

    A 68-year-old woman with painful osteolytic L2 metastases from lung adenocarcinoma was treated with MWA combined with VA. A, Preoperative axial CT shows L2 osteolytic destruction. B, A thermocouple needle was inserted and placed in proximity to the posterior vertebral body to monitor real-time temperature during MWA via the paravertebral approach. C, The MVA antenna is inserted into the lesion via a transpedicular approach. D, Postprocedural axial CT images show cement distribution in the treated vertebra.

  • FIG 2.
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    FIG 2.

    A, Changes in the median preoperative and postoperative VAS scores (P < .05 versus baseline). B, The mean (SD) of daily morphine consumption before and after the procedure. C, Changes in the median preoperative and postoperative ODI scores (P < .01 versus baseline).

  • FIG 3.
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    FIG 3.

    A 54-year-old man with painful L2 metastases from choroidal melanoma was treated with MWA and VA and developed partial hemiplegia after the procedure. A, An aggressive destructive osteolytic lesion of the L2 vertebra with posterior vertebral wall involvement and epidural compression is seen on the axial MR image. B, Sagittal CT shows the distribution of cement in the metastatic vertebra. C, Six-month follow-up axial MR imaging shows the epidural tumor shrinkage, and local tumor control was achieved.

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    Table 1:

    Baseline characteristics of the patients

    CharacteristicsNo.Percentage
    Mean age (range) (yr)62 (36–78)
    Sex
     Male5054.9%
     Female4145.1%
    Primary malignancy
     Lung3639.6%
     Breast1314.3%
     Liver55.5%
     Bile duct22.2%
     Esophagus1112.1%
     Cardia and stomach44.4%
     Colorectum55.5%
    Sarcoma22.2%
     Multiple myeloma11.1%
     Kidney22.2%
     Ureter33.3%
     Prostate11.1%
     Uterus and ovary22.2%
     Unknown primary44.4%
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    Table 2:

    Radiologic and operative characteristics

    CharacteristicsNo.Percent/Range
    Treated vertebrae (thoracic/lumbar)140 (71/69)
    No. of metastatic vertebrae treated for each patient
     Single53
     230
     35
     43
    Type of destruction (osteolytic/mixed)114/26
    Posterior wall involvement49/14035%
    Vertebral body compression52/14037%
    Ablation power (mean) (range) (W)29.3 (SD, 4.39)20–40
    Ablation time (mean) (range) (min)3.48 (SD, 1.36)2–5
    Cement filling rate of the lesion
     50%–75%3525%
     75%–90%5337.9%
     ≈100%5237.1%
    Cement leakage42/14030%
     Diskal12
     Epidural6
     Paravertebral20
     Foramina3
     Access track4
    Volume of cement for each vertebra (mean) (range) (mL)5.4 (SD, 2.4)2–8
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L. Chen, G. Hou, K. Zhang, Z. Li, S. Yang, Y. Qiu, Q. Yuan, D. Hou, X. Ye
Percutaneous CT-Guided Microwave Ablation Combined with Vertebral Augmentation for Treatment of Painful Spinal Metastases
American Journal of Neuroradiology Feb 2022, DOI: 10.3174/ajnr.A7415

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Percutaneous CT-Guided Microwave Ablation Combined with Vertebral Augmentation for Treatment of Painful Spinal Metastases
L. Chen, G. Hou, K. Zhang, Z. Li, S. Yang, Y. Qiu, Q. Yuan, D. Hou, X. Ye
American Journal of Neuroradiology Feb 2022, DOI: 10.3174/ajnr.A7415
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