Article Figures & Data
Figures
- FIG 1.
Examples of ROIs in the lateral and central eye chamber and the VB (A), the optical nerve sheath (ONS) (B), the Meckel Cave (MC), and the basal cistern (C) and lateral ventricles (D). Min indicates minimum; Max, maximum.
- FIG 2.
Image demonstrating contrast agent kinetics after injection of gadolinium in healthy patients: native scan (A), scan 20 minutes after Gd injection demonstrating the physiologic permeability of Gd in the lateral eye chamber (small arrow) (B), and physiologic, symmetric enhancement in the central eye chamber and the VB in the late scan after 120 minutes (C) (thick arrows).
- FIG 3.
Example of a patient with a disorder in the AEC on the right; native scan (A), scan 20 minutes after gadolinium injection demonstrating a higher permeability of Gd in the lateral eye chamber (small arrow) and increased Gd enhancement in the in the central eye chamber on the right (thick arrow) (B), and the VB (arrowhead) in the late scan after 120 minutes in the right eye (C).
- FIG 4.
Example of a patient with a disorder in the PEC (retinal). Native scan (A), 20 minutes after gadolinium injection demonstrating a pathologic permeability of Gd at the blood-retinal barrier (small arrows) (B), and accumulation of Gd in the VB after 120 minutes (arrowhead) demonstrating an opposite pathway of Gd (C). The physiologic enhancement in the anterior eye segment can also be seen in C, independent of the pathology of the posterior eye segment.
- FIG 5.
Relative SI 20 minutes (white boxplot) and 120 minutes (gray boxplot) after contrast application in the AC central (AC_central_1 = 20 minutes, AC_central_2 = 120 minutes), AC lateral (AC_lateral_1 = 20 minutes, AC_lateral = 120 minutes), and VB (VB_1 = 20 minutes, VB_2 = 120 minutes) in the control group and in patients with disorders in the AECs and PECs.
Tables
OP (n = 63) Nonop (n = 32) P Value Sex Male 36 (38%) 20 (21%) χ² = .811 Female 27 (28%) 12 (13%) Weight (mean) (kg) 80.31 (SD, 15.19) 80.67 (SD, 14.72) .912 Age (mean) (yr) 60.87 (SD, 16.18) 60.09 (SD, 16.67) .825 Gd (mean) (mL) 15.31 (SD, 2.65) 14.91 (SD, 3.00) .508 Comorbidity Arterial hypertension 35 (56%) 10 (31%) χ² = .015 Diabetes mellitus 12 (19%) 6 (19%) χ² = .89 Nicotine abuse 5 (8%) 3 (9%) χ² = .368 Obesity 6 (9%) 1 (3%) χ² = .238 Atherosclerosis 16 (17%) 4 (13%) χ² = .102 OSAS 2 (3%) 1 (3%) χ² = .959 Rheumatoid arthritis 9 (14%) 3 (9%) χ² = .449 Note:—OP indicates ophthalmologic pathology; Nonop, no ophthalmologic pathology; OSAS, obstructive sleep apnea syndrome.
- Table 2:
Relative SI of the control group and patients with a disorder in the AEC and PEC compared with the control groupa
ROI, Groups No. Mean SD SD Error 20 min 120 min 20 min 120 min 20 min 120 min p20 p120 AC central Control 64 0.27 1.79 0.5 1.39 0.06 0.17 AEC 30 0.84 3.40 0.79 2.21 0.14 0.40 .000 .001 PEC 96 0.51 2.49 0.66 1.80 0.07 0.18 .055 .041 AC lateral Control 64 0.29 1.10 0.62 0.99 0.08 0.12 AEC 30 0.86 1.93 0.92 1.43 0.17 0.26 .001 .005 PEC 96 0.50 1.40 0.68 1.26 0.07 0.13 .201 .241 VB Control 64 0.04 0.16 0.26 0.43 0.03 0.05 AEC 30 0.11 0.42 0.20 0.49 0.04 0.09 .020 .090 PEC 96 0.04 0.44 0.26 0.64 0.03 0.07 .169 .006 Distal optic nerve Control 64 0.31 1.46 1.16 1.23 0.14 0.15 AEC 30 0.44 1.77 0.57 1.21 0.10 0.22 .860 .699 PEC 96 0.33 1.78 0.76 1.65 0.08 0.17 .999 .308 MC Control 64 0.45 1.61 0.71 1.15 0.09 0.14 AEC 30 0.72 2.10 0.71 1.16 0.13 0.21 .138 .184 PEC 96 0.53 1.81 0.53 1.26 0.05 0.13 .812 .647 Basel cistern Control 32 0.004 0.24 0.29 0.22 0.05 0.04 AEC 15 0.15 0.38 0.22 0.38 0.06 0.09 .340 .898 PEC 48 0.85 0.37 0.33 0.63 0.05 0.09 .576 .461 Lateral ventricles Control 32 0.04 0.27 0.34 0.39 0.06 0.07 AEC 15 0.21 0.40 0.24 0.28 0.06 0.07 .210 .650 PEC 48 0.08 0.31 0.27 0.43 0.04 0.06 .945 .922 Note:—AC central indicates central aqueous chamber of the eye; AC lateral, lateral aqueous chamber of the eye; MC, Meckel cave.
↵a Reported values are estimated mean (SD), errors of SD, and P values.
