PT  - JOURNAL ARTICLE
AU  - Rabinstein, Alejandro A.
AU  - Wijdicks, Eelco F. M.
AU  - Nichols, Douglas A.
TI  - Complete Recovery after Early Intraarterial Recombinant Tissue Plasminogen Activator Thrombolysis of Carotid T Occlusion
DP  - 2002 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1596--1599
VI  - 23
IP  - 9
4099  - http://www.ajnr.org/content/23/9/1596.short
4100  - http://www.ajnr.org/content/23/9/1596.full
SO  - Am. J. Neuroradiol.2002 Oct 01; 23
AB  - Summary: Carotid T occlusion (intracranial carotid bifurcation occlusion with involvement of A1 and M1 segments) is associated with poor outcome. In most cases, treatment with intraarterial thrombolysis within a 6-hour window has been unsuccessful. We describe the case of a 26-year-old woman who presented with severe neurologic deficits (National Institutes of Health Stroke Scale score of 23) secondary to angiographically proved right carotid T occlusion. She was treated with intraarterial infusion of recombinant tissue plasminogen activator that was started less than 3 hours after symptom onset (26 mg administered during 2 hours 15 minutes). Thrombolysis resulted in recanalization of all major intracranial vessels and complete neurologic recovery. Early intraarterial thrombolysis may be effective in the treatment of patients with carotid T occlusion and should be considered for appropriate candidates.