RT Journal Article
SR Electronic
T1 Parathyroid Lesions: Characterization with Dual-Phase Arterial and Venous Enhanced CT of the Neck
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 949
OP 952
DO 10.3174/ajnr.A2885
VO 33
IS 5
A1 Gafton, A.R.
A1 Glastonbury, C.M.
A1 Eastwood, J.D.
A1 Hoang, J.K.
YR 2012
UL http://www.ajnr.org/content/33/5/949.abstract
AB SUMMARY: This clinical report describes the enhancement characteristics of hypersecreting parathyroid lesions on dual-phase neck CT. We retrospectively analyzed the enhancement characteristics of 5 pathologically confirmed PTH-secreting lesions on dual-phase CT examinations. Attenuation values were measured for PTH-secreting lesions, vascular structures (CCA and IJV), and soft tissue structures (thyroid gland, jugulodigastric lymph node, and submandibular gland). From the attenuation values, “relative enhancement washout percentage” and “tissue-vascular ratio” were calculated and compared. All lesions decreased in attenuation from arterial to venous phase, while the mean attenuation values of other soft tissue structures increased. A high relative enhancement washout percentage was correlated with parathyroid lesions (P < .006). The tissue-CCA ratio and tissue-IJV ratio for PTH-secreting lesions in the arterial phase were statistically significantly higher compared with soft tissue structures (P < .05). If these results are validated in future larger studies, noncontrast and delayed venous phases of 4D-CT could be eliminated to markedly reduce radiation exposure. CCAcommon carotid arteryHUHounsfield unitsIJVinternal jugular veinPTHparathyroid hormoneROCreceiver operating characteristic curve