RT Journal Article
SR Electronic
T1 Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1211
OP 1220
DO 10.3174/ajnr.A2621
VO 33
IS 7
A1 Hussein, H.M.
A1 Georgiadis, A.L.
A1 Qureshi, A.I.
YR 2012
UL http://www.ajnr.org/content/33/7/1211.abstract
AB SUMMARY: POC testing is defined as diagnostic testing at or near the site of patient care. Rapid measurement of the intensity of anticoagulation and, more recently, platelet inhibition allows dose titration of adjuvant medications such a heparin and antiplatelet agents during neuroendovascular procedures. However, knowledge among practicing physicians regarding the pathophysiologic basis of these measurements and variations in knowledge about the differences among devices is often limited. This review discusses the role of anticoagulation in endovascular procedures and the currently available POC tests for anticoagulation monitoring. ACTactivated clotting timeAnti-Xaquantitative chromogenic heparin assayaPTTactivated partial thromboplastin timeATantithrombinCIconfidence intervalGP IIb/IIIaglycoprotein IIb/IIIaHemonox-CTHemonox clotting timeHITheparin-induced thrombocytopeniaHMTHeparin Management TestIVintravenousLMWHlow-molecular-weight heparinMImyocardial infarctionORodds ratioPCIpercutaneous coronary interventionPOCpoint of careUFHunfractionated heparin