PT - JOURNAL ARTICLE AU - Yousem, D M AU - Atlas, S W AU - Grossman, R I AU - Sergott, R C AU - Savino, P J AU - Bosley, T M TI - MR imaging of Tolosa-Hunt syndrome. DP - 1989 Nov 01 TA - American Journal of Neuroradiology PG - 1181--1184 VI - 10 IP - 6 4099 - http://www.ajnr.org/content/10/6/1181.short 4100 - http://www.ajnr.org/content/10/6/1181.full SO - Am. J. Neuroradiol.1989 Nov 01; 10 AB - The Tolosa-Hunt syndrome consists of painful ophthalmoplegia caused by cavernous sinus inflammation, which is responsive to steroid therapy. The MR features of 11 patients with the clinical diagnosis of Tolosa-Hunt syndrome were studied. Two patients had normal MR studies of the orbit and cavernous sinuses. In nine patients, abnormal signal and/or mass lesions were seen in the cavernous sinuses; in eight cases, the abnormality was hypointense relative to fat and isointense with muscle on short TR/TE images and isointense with fat on long TR/TE scans. Extension into the orbital apex was seen in eight cases. In six of nine cases the affected cavernous sinus was enlarged; in five of nine it had a convex outer margin. One patient had a thrombosed cavernous sinus and superior ophthalmic vein in addition to a cavernous sinus soft-tissue mass. The signal intensity of Tolosa-Hunt syndrome in this limited series was similar to that of orbital pseudotumor and is confined to a limited differential diagnosis, which includes meningioma, lymphoma, and sarcoidosis.