PT - JOURNAL ARTICLE AU - Duprez, T P AU - Grandin, C B AU - Bonnier, C AU - Thauvoy, C W AU - Gadisseux, J F AU - Dutrieux, J L AU - Evrard, P TI - Whipple disease confined to the central nervous system in childhood. DP - 1996 Sep 01 TA - American Journal of Neuroradiology PG - 1589--1591 VI - 17 IP - 8 4099 - http://www.ajnr.org/content/17/8/1589.short 4100 - http://www.ajnr.org/content/17/8/1589.full SO - Am. J. Neuroradiol.1996 Sep 01; 17 AB - In a case of pediatric Whipple disease confined to the central nervous system, white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images, and showed slight peripheral enhancement on delayed contrast-enhanced T1-weighted images. On MR studies obtained 3 and 6 months after antibiotic therapy, the lesions had decreased in size and no longer enhanced. They became progressively less hypointense on T1-weighted images and less hyperintense on T2-weighted images.