RT Journal Article SR Electronic T1 Telangiectatic osteosarcoma of the skull base. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 754 OP 757 VO 19 IS 4 A1 Whitehead, R E A1 Melhem, E R A1 Kasznica, J A1 Eustace, S YR 1998 UL http://www.ajnr.org/content/19/4/754.abstract AB We present a patient with a distinctive lesion of the skull base, which, at imaging, showed expansile destruction of the sphenoid bone, hemorrhage with fluid-fluid levels, and contrast enhancement of a solid portion. These features ordinarily suggest either giant cell tumor or aneurysmal bone cyst; however, pathologic examination confirmed instead a rare variant of osteosarcoma of the telangiectatic type. Although imaging findings can indicate any of these possibilities, biopsy is an essential step in arriving at the diagnosis.