RT Journal Article SR Electronic T1 Spontaneous labyrinthine hemorrhage in sickle cell disease. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1437 OP 1440 VO 19 IS 8 A1 Whitehead, R E A1 MacDonald, C B A1 Melhem, E R A1 McMahon, L YR 1998 UL http://www.ajnr.org/content/19/8/1437.abstract AB We report the clinical and MR imaging findings in two African-American patients with manifestations of sickle cell disease affecting the inner ear. Both suffered sudden-onset sensorineural hearing loss and vestibular symptoms, and both had high labyrinthine signal on T1-weighted MR images attributed to labyrinthine hemorrhage. Follow-up studies of the first patient revealed a decrease in abnormal vestibular signal. Careful attention to the labyrinth on T1-weighted MR images can reveal vestibulocochlear clinical findings in sickle cell patients, with important implications for management and prognosis.