PT  - JOURNAL ARTICLE
AU  - Tsuyuguchi, Naohiro
AU  - Matsuoka, Yoshimi
AU  - Sunada, Ichiro
AU  - Matsusaka, Yasuhiro
AU  - Haque, Moududul
TI  - Evaluation of Pleomorphic Xanthoastrocytoma by Use of Positron Emission Tomography with [18-F]-Fluorodeoxyglucose and [11C]-Methionine Tracers
DP  - 2001 Feb 01
TA  - American Journal of Neuroradiology
PG  - 311--313
VI  - 22
IP  - 2
4099  - http://www.ajnr.org/content/22/2/311.short
4100  - http://www.ajnr.org/content/22/2/311.full
SO  - Am. J. Neuroradiol.2001 Feb 01; 22
AB  - Summary: We present a case of pleomorphic xanthoastrocytoma (PXA) in a patient with temporal lobe seizures. Imaging sequences included MR, and results of positron emission tomography (PET) with [18F]-fluorodeoxyglucose (FDG) and [11C]-methionine (Met) tracers revealed a hypermetabolic region equivalent or nearly equivalent to normal cerebral cortex, suggesting that the tumor might have malignant potential. Histopathologic findings indicated low-grade glioma. The mechanism for glucose hypermetabolic activity of PXA is not clear; however, the positive findings obtained from FDG-PET may not always indicate the degree of malignancy associated with PXA.