RT Journal Article
SR Electronic
T1 Secondary Supratentorial Primitive Neuroectodermal Tumor following Irradiation in a Patient with Low-Grade Astrocytoma
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 160
OP 162
VO 26
IS 1
A1 Chen, Allan Y.
A1 Lee, Haidy
A1 Hartman, Jonathan
A1 Greco, Claudia
A1 Ryu, Janice K.
A1 O’Donnell, Robert
A1 Boggan, James
YR 2005
UL http://www.ajnr.org/content/26/1/160.abstract
AB Summary: We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, PNET needs to be included in the differential diagnoses for previously irradiated patients, who develop recurrent brain tumors in the presence of uncharacteristic imaging features.