PT - JOURNAL ARTICLE AU - Kitajima, Mika AU - Korogi, Yukunori AU - Yamura, Masayuki AU - Ikushima, Ichiro AU - Hayashida, Yoshiko AU - Ando, Yukio AU - Uchino, Makoto AU - Yamashita, Yasuyuki TI - Familial Amyloid Polyneuropathy: Hypertrophy of Ligaments Supporting the Spinal Cord DP - 2004 Oct 01 TA - American Journal of Neuroradiology PG - 1599--1602 VI - 25 IP - 9 4099 - http://www.ajnr.org/content/25/9/1599.short 4100 - http://www.ajnr.org/content/25/9/1599.full SO - Am. J. Neuroradiol.2004 Oct 01; 25 AB - Summary: We describe characteristic spinal MR findings of two cases of familial amyloid polyneuropathy (FAP). Both cases showed leptomeningeal enhancement on contrast-enhanced T1-weighted image. In addition, three-dimensional constructive interference in steady-state imaging demonstrated thickening of the ligaments, other connective tissues within the spinal canal, dura matter, and dorsal nerve roots. These findings in FAP are felt to represent amyloid deposition.