RT Journal Article
SR Electronic
T1 Pitfalls in Lactate Measurements at 3T
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 895
OP 901
VO 27
IS 4
A1 Lange, T.
A1 Dydak, U.
A1 Roberts, T.P.L.
A1 Rowley, H.A.
A1 Bjeljac, M.
A1 Boesiger, P.
YR 2006
UL http://www.ajnr.org/content/27/4/895.abstract
AB SUMMARY: In clinical MR spectroscopy at higher field strengths, lactate may show reduced or absent signal intensity at an echo time of 144 ms. Although this false-negative result may be predicted from theory, experimental verification and clinical impact have not been fully established. Using scanners from 3 major vendors, spectra from phantoms and patients demonstrate the lactate signal loss and potential error in interpretation. Strategies are discussed to overcome, or at least alleviate, this problem.