RT Journal Article SR Electronic T1 Acute Stroke Imaging Research Roadmap JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP e23 OP e30 VO 29 IS 5 A1 Wintermark, Max A1 Albers, Gregory W. A1 Alexandrov, Andrei V. A1 Alger, Jeffry R. A1 Bammer, Roland A1 Baron, Jean-Claude A1 Davis, Stephen A1 Demaerschalk, Bart M. A1 Derdeyn, Colin P. A1 Donnan, Geoffrey A. A1 Eastwood, James D. A1 Fiebach, Jochen B. A1 Fisher, Marc A1 Furie, Karen L. A1 Goldmakher, Gregory V. A1 Hacke, Werner A1 Kidwell, Chelsea S. A1 Kloska, Stephan P. A1 Köhrmann, Martin A1 Koroshetz, Walter A1 Lee, Ting-Yim A1 Lees, Kennedy R. A1 Lev, Michael H. A1 Liebeskind, David S. A1 Ostergaard, Leif A1 Powers, William J. A1 Provenzale, James A1 Schellinger, Peter A1 Silbergleit, Robert A1 Sorensen, Alma Gregory A1 Wardlaw, Joanna A1 Wu, Ona A1 Warach, Steven YR 2008 UL http://www.ajnr.org/content/29/5/e23.abstract AB The recent “Advanced Neuroimaging for Acute Stroke Treatment” meeting on September 7 and 8, 2007 in Washington DC, brought together stroke neurologists, neuroradiologists, emergency physicians, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Biomedical Imaging and Bioengineering (NIBIB), industry representatives, and members of the US Food and Drug Administration (FDA) to discuss the role of advanced neuroimaging in acute stroke treatment. The goals of the meeting were to assess state-of-the-art practice in terms of acute stroke imaging research and to propose specific recommendations regarding: (1) the standardization of perfusion and penumbral imaging techniques, (2) the validation of the accuracy and clinical utility of imaging markers of the ischemic penumbra, (3) the validation of imaging biomarkers relevant to clinical outcomes, and (4) the creation of a central repository to achieve these goals. The present article summarizes these recommendations and examines practical steps to achieve them.