PT  - JOURNAL ARTICLE
AU  - Liu, H.-S.
AU  - Chung, H.-W.
AU  - Juan, C.-J.
AU  - Tsai, S.-Y.
AU  - Wang, C.-Y.
AU  - Chan, C.-C.
AU  - Huang, G.-S.
AU  - Chou, M.-C.
AU  - Lee, C.-S.
AU  - Ko, C.-W.
AU  - Cho, N.-Y.
AU  - Chen, C.-Y.
TI  - Anomalous J-Modulation Effects on Amino Acids in Clinical 3T MR Spectroscopy
AID  - 10.3174/ajnr.A1131
DP  - 2008 Oct 01
TA  - American Journal of Neuroradiology
PG  - 1644--1648
VI  - 29
IP  - 9
4099  - http://www.ajnr.org/content/29/9/1644.short
4100  - http://www.ajnr.org/content/29/9/1644.full
SO  - Am. J. Neuroradiol.2008 Oct 01; 29
AB  - SUMMARY: The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved 1H spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.