RT Journal Article
SR Electronic
T1 Anomalous J-Modulation Effects on Amino Acids in Clinical 3T MR Spectroscopy
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1644
OP 1648
DO 10.3174/ajnr.A1131
VO 29
IS 9
A1 Liu, H.-S.
A1 Chung, H.-W.
A1 Juan, C.-J.
A1 Tsai, S.-Y.
A1 Wang, C.-Y.
A1 Chan, C.-C.
A1 Huang, G.-S.
A1 Chou, M.-C.
A1 Lee, C.-S.
A1 Ko, C.-W.
A1 Cho, N.-Y.
A1 Chen, C.-Y.
YR 2008
UL http://www.ajnr.org/content/29/9/1644.abstract
AB SUMMARY: The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved 1H spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.