PT  - JOURNAL ARTICLE
AU  - Konstas, A.A.
AU  - Goldmakher, G.V.
AU  - Lee, T.-Y.
AU  - Lev, M.H.
TI  - Theoretic Basis and Technical Implementations of CT Perfusion in Acute Ischemic Stroke, Part 1: Theoretic Basis
AID  - 10.3174/ajnr.A1487
DP  - 2009 Apr 01
TA  - American Journal of Neuroradiology
PG  - 662--668
VI  - 30
IP  - 4
4099  - http://www.ajnr.org/content/30/4/662.short
4100  - http://www.ajnr.org/content/30/4/662.full
SO  - Am. J. Neuroradiol.2009 Apr 01; 30
AB  - SUMMARY: CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct “core”) and the severely ischemic but potentially salvageable tissue (“penumbra”). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.