PT  - JOURNAL ARTICLE
AU  - Salgado, R.A.
AU  - Jorens, P.G.
AU  - Baar, I.
AU  - Cras, P.
AU  - Hans, G.
AU  - Parizel, P.M.
TI  - Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings
AID  - 10.3174/ajnr.A1889
DP  - 2010 Mar 01
TA  - American Journal of Neuroradiology
PG  - 565--566
VI  - 31
IP  - 3
4099  - http://www.ajnr.org/content/31/3/565.short
4100  - http://www.ajnr.org/content/31/3/565.full
SO  - Am. J. Neuroradiol.2010 Mar 01; 31
AB  - SUMMARY: We report the clinical, MR imaging, and proton MR spectroscopy findings in a middle-aged woman with proved methadone-induced toxic leukoencephalopathy. The imaging characteristics of this unusual condition have been reported only rarely in the medical literature. We show that the imaging findings in methadone-induced toxic leukoencephalopathy are similar, though not identical, to previously reported cases of neurologic deterioration due to heroin inhalation. ChocholineCrcreatineFLAIRfluid-attenuated inversion recoveryNAAN-acetylaspartate