RT Journal Article
SR Electronic
T1 Endovascular Stroke Treatment Today
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 238
OP 243
DO 10.3174/ajnr.A2346
VO 32
IS 2
A1 Grunwald, I.Q.
A1 Wakhloo, A.K.
A1 Walter, S.
A1 Molyneux, A.J.
A1 Byrne, J.V.
A1 Nagel, S.
A1 Kühn, A.L.
A1 Papadakis, M.
A1 Fassbender, K.
A1 Balami, J.S.
A1 Roffi, M.
A1 Sievert, H.
A1 Buchan, A.
YR 2011
UL http://www.ajnr.org/content/32/2/238.abstract
AB SUMMARY: The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Compelling evidence of their recanalization efficacy comes from current mechanical embolectomy trials. In addition to allowing an extension of the therapeutic time window, mechanical recanalization devices can be used without adjuvant thrombolytic therapy, thus diminishing the intracranial bleeding risk. Therefore, these devices are particularly suitable in patients in whom thrombolytic therapy is contraindicated. IV and IA thrombolysis and bridging therapy are viable options in acute stroke treatment. Mechanical recanalization devices can potentially have a clinically relevant impact in the interventional treatment of stroke, but at the present time, a randomized study would be beneficial. CEconformité européenneDEDASDose Escalation of Desmoteplase for Acute Ischemic StrokeDIASDesmoteplase in Acute Ischemic StrokeDWIdiffusion-weighted imagingECASSEuropean Cooperative Acute Stroke StudiesEPITHETEchoplanar Imaging Thrombolytic Evaluation TrialIAintra-arterialIMSInterventional Management of StrokeIVintravenousMCAmiddle cerebral arterymRSmodified Rankin ScaleNIHSSNational Institutes of Health Stroke ScalePROACTProlyse in Acute Cerebral ThromboembolismPWIperfusion-weighted imagingrtPArecombinant tissue plasminogen activatorTIMIThrombolysis in Myocardial Infarction