RT Journal Article SR Electronic T1 Pineal Region Tumors: Computed Tomographic-Pathologic Spectrum JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 415 OP 420 VO 2 IS 5 A1 Futrell, Nancy N. A1 Osborn, Anne G. A1 Cheson, Bruce D. YR 1981 UL http://www.ajnr.org/content/2/5/415.abstract AB While several computed tomographic (CT) studies of posterior third ventricular neoplasms have included descriptions of pineal tumors, few reports have concentrated on these uncommon lesions. Some authors have asserted that the CT appearance of many pineal tumors is virtually pathognomonic. A series of nine biopsy-proved pineal gland and eight other presumed tumors is presented that illustrates their remarkable heterogeneity in both histopathologic and CT appearance. These tumors included germinomas, teratocarcinomas, hamartomas, and other varieties. They had variable margination, attenuation, calcification, and suprasellar extension. Germinomas have the best response to radiation therapy. Biopsy of pineal reg ion tumors is now feasible and is recommended for treatment planning.