RT Journal Article
SR Electronic
T1 The Characteristics and Risk Factors of Headache Development after the Coil Embolization of an Unruptured Aneurysm
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1676
OP 1678
DO 10.3174/ajnr.A3018
VO 33
IS 9
A1 Hwang, G.
A1 Jeong, E.-A.
A1 Sohn, J.H.
A1 Park, H.
A1 Bang, J.S.
A1 Jin, S.-C.
A1 Kim, B.C.
A1 Oh, C.W.
A1 Kwon, O.-K.
YR 2012
UL http://www.ajnr.org/content/33/9/1676.abstract
AB BACKGROUND AND PURPOSE: Development of a headache after aneurysm coil embolization is not uncommon but has received little attention. The authors prospectively analyze the characteristics and risk factors of a headache after coiling in patients treated for an unruptured cerebral aneurysm. MATERIALS AND METHODS: Ninety patients treated for an unruptured cerebral aneurysm over a period of 1 year, and without a headache history within a month before coiling, were enrolled in this study. All coilings were successfully performed without neurologic complications. After coiling, headache development and intensities were recorded. RESULTS: Fifty (55.6%) patients experienced a headache (VAS score, 4.5 ± 2.02) at 7.9 (range, 0–72) hours, on average, after coiling, and all headaches resolved within an average of 73.0 (range, 3–312) hours. Univariate analysis showed that the following were significantly associated with the development of a headache: age ≤50 years (OR 4.636, 95% CI, 1.414–15.198), hypertension (OR 0.232, 95% CI, 0.095–0.571), a packing attenuation of >25% (OR 3.619, 95% CI, 1.428–9.174), and a previous headache history (OR 2.769, 95% CI, 1.120–6.849). However, binary logistic regression showed that only a packing attenuation of >25% (P = .013, adjusted OR 3.774, 95% CI, 1.320–10.790) and no history of hypertension (P = .019, adjusted OR 3.515, 95% CI, 1.233–10.021) were independently associated with the development of a headache. CONCLUSIONS: A headache frequently developed after the coiling of unruptured aneurysms. However, headaches were relatively benign and resolved within several days. The present study shows that no hypertension history and a packing attenuation of >25% are risk factors of headache development. CIconfidence intervalNSAIDnonsteroidal anti-inflammatory drugORodds ratioVASVisual Analogue Scale