RT Journal Article
SR Electronic
T1 Head and Neck Tumors: Assessment of Perfusion-Related Parameters and Diffusion Coefficients Based on the Intravoxel Incoherent Motion Model
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 410
OP 416
DO 10.3174/ajnr.A3227
VO 34
IS 2
A1 Sumi, M.
A1 Nakamura, T.
YR 2013
UL http://www.ajnr.org/content/34/2/410.abstract
AB BACKGROUND AND PURPOSE: IVIM MR imaging provides perfusion and diffusion information with a single diffusion-weighted MR image. We determined whether PP and D differ among various types of head and neck tumors. MATERIALS AND METHODS: The study cohort included 123 head and neck tumors: 30 SCCs, 28 benign and 20 malignant SG tumors, 36 lymphomas, and 9 schwannomas. The D and PP values were determined by using b-values of 0, 500, and 1000 s/mm2 based on the IVIM model. RESULTS: The PP values (lymphomas, 0.09 ± 0.04; SCCs, 0.15 ± 0.04; and malignant SG tumors, 0.22 ± 0.07) and D values (0.47 ± 0.07 × 10−3 mm2/s, 0.82 ± 0.17 × 10−3 mm2/s, and 1.03 ± 0.16 × 10−3 mm2/s, respectively) were significantly different among the malignant tumors (P < .01). These values were also significantly different between pleomorphic adenomas (0.13 ± 0.02 and 1.44 ± 0.39 × 10−3 mm2/s) and Warthin tumors (0.19 ± 0.04 and 0.73 ± 0.22 × 10−3 mm2/s) (P < .001). The PP values of malignant SG tumors were significantly different from those of pleomorphic adenomas (P = .001) and the D values of the malignant SG tumors were significantly different from those of pleomorphic adenomas (P = .002) and Warthin tumors (P = .007). Schwannomas had large PP (0.23 ± 0.08) and D values (1.26 ± 0.20 × 10−3 mm2/s), greatly overlapping those of some SG tumor types. CONCLUSIONS: Head and neck tumors had distinctive PP and D values by using IVIM MR imaging. Ddiffusion coefficientD*perfusion-related incoherent microcirculationfperfusion factorIVIMintravoxel incoherent motionPPperfusion-related parameterSCCsquamous cell carcinomaSGsalivary gland