PT  - JOURNAL ARTICLE
AU  - Hanafi, R.
AU  - Roger, P.-A.
AU  - Perin, B.
AU  - Kuchcinski, G.
AU  - Deleval, N.
AU  - Dallery, F.
AU  - Michel, D.
AU  - Hacein-Bey, L.
AU  - Pruvo, J.-P.
AU  - Outteryck, O.
AU  - Constans, J.-M.
TI  - COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern
AID  - 10.3174/ajnr.A6651
DP  - 2020 Aug 01
TA  - American Journal of Neuroradiology
PG  - 1384--1387
VI  - 41
IP  - 8
4099  - http://www.ajnr.org/content/41/8/1384.short
4100  - http://www.ajnr.org/content/41/8/1384.full
SO  - Am. J. Neuroradiol.2020 Aug 01; 41
AB  - SUMMARY: Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of “endotheliitis” associated with this novel coronavirus.ACE2angiotensin converting enzyme 2COVID-19coronavirus disease 2019SARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2