RT Journal Article
SR Electronic
T1 Shape Modification is Common in Woven EndoBridge–Treated Intracranial Aneurysms: A Longitudinal Quantitative Analysis Study
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1652
OP 1656
DO 10.3174/ajnr.A6669
VO 41
IS 9
A1 Rosskopf, J.
A1 Braun, M.
A1 Dreyhaupt, J.
A1 Beer, M.
A1 Schmitz, B.L.
A1 Ozpeynirci, Y.
YR 2020
UL http://www.ajnr.org/content/41/9/1652.abstract
AB BACKGROUND AND PURPOSE: After endovascular treatment of intracranial aneurysms with the Woven EndoBridge (WEB) device, worsening of aneurysm occlusion or re-opening was reported to be possibly associated with WEB shape modification. This study analyzed quantitatively the WEB shape modification with time in association with anatomic results.MATERIALS AND METHODS: Thirty patients with 32 WEB-treated intracranial aneurysms fulfilled the inclusion criteria of cranial CT at baseline (day of intervention) and a follow-up CT at least >1 months' later (median follow-up time, 11.4 months; interquartile range, 6.5–21.5 months). Adequate occlusion was observed in 84.4%, and aneurysm remnant, in 15.6%. WEB shape modification was quantified by a semiautomated approach on CT scans. Time courses were evaluated graphically and analytically; association analyses were performed by linear mixed-effects regression models.RESULTS: In 29/32 WEB devices (90.6%), the reduction in height was found to be at least 5%. The decrease in height with time was significantly associated with the time interval in days since the intervention (P < .0001): A stronger decrease in WEB height was associated with a longer time since the intervention (median reduction in 1 year, 19.2%; range, 8.6%–52.3%). No significant association was found with the quality of aneurysm occlusion, device size, rupture status of the aneurysm, aneurysm location, and reintervention rate.CONCLUSIONS: Shape modification was common in WEB-treated intracranial aneurysms with a median height reduction of 19.2% in 1 year. The quality of aneurysm occlusion was not associated with WEB modification.ASAacetylsalicylic acidSLsingle-layerSLSsingle-layer sphereWEBWoven EndoBridge