PT - JOURNAL ARTICLE AU - Gaur, P. AU - Dixon, L. AU - Jones, B. AU - Lyall, H. AU - Jan, W. TI - COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum AID - 10.3174/ajnr.A6713 DP - 2020 Oct 01 TA - American Journal of Neuroradiology PG - 1905--1907 VI - 41 IP - 10 4099 - http://www.ajnr.org/content/41/10/1905.short 4100 - http://www.ajnr.org/content/41/10/1905.full SO - Am. J. Neuroradiol.2020 Oct 01; 41 AB - SUMMARY: There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.CLOCCcytotoxic lesions of the corpus callosumCOVID-19coronavirus disease 2019CRPC-reactive proteinRT-PCRreal-time reverse transcriptase polymerase chain reactionSARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2