PT  - JOURNAL ARTICLE
AU  - Barkovich, A. James
AU  - Norman, David
TI  - Absence of the Septum Pellucidum: A Useful Sign in the Diagnosis of Congenital Brain Malformations
DP  - 1988 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1107--1114
VI  - 9
IP  - 6
4099  - http://www.ajnr.org/content/9/6/1107.short
4100  - http://www.ajnr.org/content/9/6/1107.full
SO  - Am. J. Neuroradiol.1988 Nov 01; 9
AB  - In a review of more than 2000 MR images of the brain we identified 35 patients with absence of the septum pellucidum. These patients were divided into seven basic groups as follows: septooptic dysplasia; schizencephaly; holoprosencephaly; agenesis of the corpus callosum; chronic, severe hydrocephalus; basilar encephaloceles; and porencephaly/hydranencephaly. Absence of the septum pellucidum was never seen as an isolated finding. By using data gathered from the review of the MR scans of patients in this study, we devised a diagnostic algorithm to aid in the classification of these patients. Absence of the septum pellucidum can provide a valuable clue to the diagnosis of malformations of the brain.