PT  - JOURNAL ARTICLE
AU  - Baek, H.J.
AU  - Heo, Y.J.
AU  - Kim, D.
AU  - Yun, S.Y.
AU  - Baek, J.W.
AU  - Jeong, H.W.
AU  - Choo, H.J.
AU  - Lee, J.Y.
AU  - Oh, S.-I.
TI  - Usefulness of Wave-CAIPI for Postcontrast 3D T1-SPACE in the Evaluation of Brain Metastases
AID  - 10.3174/ajnr.A7520
DP  - 2022 Jun 01
TA  - American Journal of Neuroradiology
PG  - 857--863
VI  - 43
IP  - 6
4099  - http://www.ajnr.org/content/43/6/857.short
4100  - http://www.ajnr.org/content/43/6/857.full
SO  - Am. J. Neuroradiol.2022 Jun 01; 43
AB  - BACKGROUND AND PURPOSE: High-resolution postcontrast 3D T1WI is a widely used sequence for evaluating brain metastasis, despite the long scan time. This study aimed to compare highly accelerated postcontrast 3D T1-weighted sampling perfection with application-optimized contrasts by using different flip angle evolution by using wave-controlled aliasing in parallel imaging (wave-T1-SPACE) with the commonly used standard high-resolution postcontrast 3D T1-SPACE for the evaluation of brain metastases.MATERIALS AND METHODS: Among the 387 patients who underwent postcontrast wave-T1-SPACE and standard SPACE, 56 patients with suspected brain metastases were retrospectively included. Two neuroradiologists assessed the number of enhancing lesions according to lesion size, contrast-to-noise ratiolesion/parenchyma, contrast-to-noise ratiowhite matter/gray matter, contrast ratiolesion/parenchyma, and overall image quality for the 2 different sequences.RESULTS: Although there was no significant difference in the evaluation of larger enhancing lesions (>5 mm) between the 2 different sequences (P = .66 for observer 1, P = .26 for observer 2), wave-T1-SPACE showed a significantly lower number of smaller enhancing lesions (<5 mm) than standard SPACE (1.61 [SD, 0.29] versus 2.84 [SD, 0.47] for observer 1; 1.41 [SD, 0.19] versus 2.68 [SD, 0.43] for observer 2). Furthermore, mean contrast-to-noise ratiolesion/parenchyma and overall image quality of wave-T1-SPACE were significantly lower than those in standard SPACE.CONCLUSIONS: Postcontrast wave-T1-SPACE showed comparable diagnostic performance for larger enhancing lesions (>5 mm) and marked scan time reduction compared with standard SPACE. However, postcontrast wave-T1-SPACE showed underestimation of smaller enhancing lesions (<5 mm) and lower image quality than standard SPACE. Therefore, postcontrast wave-T1-SPACE should be interpreted carefully in the evaluation of brain metastasis.CNRcontrast-to-noise ratioCRcontrast ratioDANTEdelay alternating with nutation for tailored excitationSPACEsampling perfection with application-optimized contrasts by using different flip angle evolutionwave-CAIPIwave-controlled aliasing in parallel imaging