PT - JOURNAL ARTICLE AU - Huls, S.J. AU - Shlapak, D.P. AU - Kim, D.K. AU - Leng, S. AU - Carr, C.M. TI - Utility of Dual-Energy CT to Improve Diagnosis of CSF Leaks on CT Myelography following Lateral Decubitus Digital Subtraction Myelography with Negative Findings AID - 10.3174/ajnr.A7628 DP - 2022 Oct 01 TA - American Journal of Neuroradiology PG - 1539--1543 VI - 43 IP - 10 4099 - http://www.ajnr.org/content/43/10/1539.short 4100 - http://www.ajnr.org/content/43/10/1539.full SO - Am. J. Neuroradiol.2022 Oct 01; 43 AB - SUMMARY: CSF leaks, including CSF-venous fistulas, which cause spontaneous intracranial hypotension, remain difficult to diagnose, even on digital subtraction myelography and CT myelography. Dual-energy CT technology has been used to improve diagnostic utility within multiple organ systems. The capability of dual-energy CT to create virtual monoenergetic images can be leveraged to increase conspicuity of contrast in CSF-venous fistulas and direct epidural CSF leakage to improve the diagnostic utility of CT myelography. Six cases (in 5 patients) are shown in which virtual monoenergetic images demonstrate a leak location that was either occult or poorly visible on high- or low-kilovolt series. This clinical report describes the novel application of dual-energy CT for the detection of subtle CSF leaks including CSF-venous fistulas.CTDIvolvolume CT dose indexCTMCT myelographyCVFCSF-venous fistulaDECTdual-energy CTDSMdigital subtraction myelographyLDDSMlateral decubitus digital subtraction myelographySIHspontaneous intracranial hypotensionVMIvirtual monoenergetic images