RT Journal Article SR Electronic T1 De Novo Formation of Idiopathic Spinal Cord Herniation JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1385 OP 1387 DO 10.3174/ajnr.A8338 VO 45 IS 9 A1 Schievink, Wouter I. A1 Maya, Marcel M. A1 Nuño, Miriam YR 2024 UL http://www.ajnr.org/content/45/9/1385.abstract AB SUMMARY: We investigated whether idiopathic spinal cord herniation is a congenital or acquired condition and undertook a study to determine the risk of developing iSCH in patients with persistent ventral spinal CSF leaks. De novo formation of iSCH was established among all 6 patients with iSCH who had undergone prior spinal imaging for symptoms unrelated to iSCH. Among 51 patients with persistent ventral spinal CSF leaks, iSCH developed in 2 patients (probability increased from 0% at 5 years to 9.4% at 10 years). This study shows that iSCH is an acquired condition, and early treatment of ventral CSF leaks offers a unique opportunity to prevent neurologic disability.iSCHidiopathic spinal cord herniationSIHspontaneous intracranial hypotensionSCHspinal cord herniationSDstandard deviation