RT Journal Article SR Electronic T1 Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 160 OP 165 DO 10.3174/ajnr.A8521 VO 46 IS 1 A1 Eldaya, Rami W. A1 Kaya, Diana A1 Williams, Michelle A1 Calle, Susana A1 Schellingerhout, Dawid YR 2025 UL http://www.ajnr.org/content/46/1/160.abstract AB SUMMARY: High-grade gliomas are the most frequent primary brain tumors, yet extraneural metastasis is exceedingly rare. This is in part secondary to the relatively poor survival of these patients and likely the shielding effect of the blood-brain barrier. Given the rarity of extraneural metastasis, the pathophysiology and imaging appearance of extraneural metastasis is under-reported and poorly understood. In this case series we present 6 patients with pathology-confirmed high-grade glioma and extraneural head and neck metastasis. We highlight imaging features of metastasis on CT, MRI, and PET/CT. We also explore potential correlations and pathophysiology of high-grade glioma metastasis to the head and neck region.IQRinterquartile rangeUSultrasound