PT  - JOURNAL ARTICLE
AU  - Cogswell, Petrice M.
AU  - Pillai, Jay J.
AU  - Lanzino, Giuseppe
AU  - Flemming, Kelly D.
TI  - Prevalence of Developmental Venous Anomalies in Association with Sporadic Cavernous Malformations on 7T MRI
AID  - 10.3174/ajnr.A8072
DP  - 2024 Jan 01
TA  - American Journal of Neuroradiology
PG  - 72--75
VI  - 45
IP  - 1
4099  - http://www.ajnr.org/content/45/1/72.short
4100  - http://www.ajnr.org/content/45/1/72.full
SO  - Am. J. Neuroradiol.2024 Jan 01; 45
AB  - BACKGROUND AND PURPOSE: The etiology of sporadic cavernous malformations is not well-understood. However, recent evidence suggests that they may arise from a developmental venous anomaly. The goal of this study was to evaluate the prevalence of developmental venous anomalies associated with sporadic cavernous malformations using 7T MR imaging.MATERIALS AND METHODS: We retrospectively identified patients with a sporadic cavernous malformation imaged with 7T MR imaging between August 2019 and July 2022. Two raters determined whether a developmental venous anomaly was associated with each malformation.RESULTS: The study included 59 patients with a total of 61 cavernous malformations. Of the sixty-one, 44 (72%) had an associated developmental venous anomaly. An associated anomaly was most common for cavernous malformations in the brainstem (88%) compared with the cerebral hemispheres or cerebellum (60%–67%).CONCLUSIONS: By means of high-quality 7T imaging, most patients with a sporadic cavernous malformation were found to have an associated developmental venous anomaly. These findings support the hypothesis that cavernous malformations may arise secondary to hemodynamic abnormalities.CMcavernous malformationDVAdevelopmental venous anomalyVMvenous malformation