PT - JOURNAL ARTICLE AU - Casasco, Alfredo AU - Houdart, Emmanuel AU - Biondi, Alessandra AU - Jhaveri, Harish S. AU - Herbreteau, Denis AU - Aymard, Armand AU - Merland, Jean-Jacques TI - Major Complications of Percutaneous Embolization of Skull-Base Tumors DP - 1999 Jan 01 TA - American Journal of Neuroradiology PG - 179--181 VI - 20 IP - 1 4099 - http://www.ajnr.org/content/20/1/179.short 4100 - http://www.ajnr.org/content/20/1/179.full SO - Am. J. Neuroradiol.1999 Jan 01; 20 AB - Summary: The technique of direct intratumoral injection of permanent liquid polymerizing agent was initially described in 1994 and has evolved significantly with experience. We report complications that occurred in two patients during injection of Histoacryl and offer suggestions to prevent such complications in the future. In one patient, the glue settled in the right middle cerebral artery; in the second, the glue entered the left ophthalmic artery through a collateral branch. Although the fundamental injection technique has not changed, we suggest additional precautions and modifications to make this procedure a safer and more valuable element in the overall management of patients with difficult skull-base tumors.