RT Journal Article
SR Electronic
T1 An Automated Technique for Measuring Hippocampal Volumes from MR Imaging Studies
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1686
OP 1689
VO 22
IS 9
A1 Gosche, Karen M.
A1 Mortimer, James A.
A1 Smith, Charles D.
A1 Markesbery, William R.
A1 Snowdon, David A.
YR 2001
UL http://www.ajnr.org/content/22/9/1686.abstract
AB Summary: We describe an automated volumetric measure of the hippocampus obtained with software called the Knowledge-Guided MRI Analysis Program (KGMAP). Postmortem MR images from 56 participants in the Nun Study were used to validate the measure. KGMAP-determined volumes strongly correlated with those obtained with manual tracings and neurofibrillary pathologic findings of Alzheimer disease in the hippocampus. KGMAP provides a rapid and accurate estimate of hippocampal volume that is suitable for use in clinical practice.