PT  - JOURNAL ARTICLE
AU  - Chen, Allan Y.
AU  - Lee, Haidy
AU  - Hartman, Jonathan
AU  - Greco, Claudia
AU  - Ryu, Janice K.
AU  - O’Donnell, Robert
AU  - Boggan, James
TI  - Secondary Supratentorial Primitive Neuroectodermal Tumor following Irradiation in a Patient with Low-Grade Astrocytoma
DP  - 2005 Jan 01
TA  - American Journal of Neuroradiology
PG  - 160--162
VI  - 26
IP  - 1
4099  - http://www.ajnr.org/content/26/1/160.short
4100  - http://www.ajnr.org/content/26/1/160.full
SO  - Am. J. Neuroradiol.2005 Jan 01; 26
AB  - Summary: We report a case of a supratentorial primitive neuroectodermal tumor (PNET) that occurred 12 years after cranial irradiation for a grade II astrocytoma. Neuroimaging was unable to distinguish between a recurrence of the original neoplasm and the development of a new, distinct entity. Pathologic review assisted by immunohistochemical staining, however, revealed a high-grade PNET. Although rare, PNET needs to be included in the differential diagnoses for previously irradiated patients, who develop recurrent brain tumors in the presence of uncharacteristic imaging features.