PT  - JOURNAL ARTICLE
AU  - Widen, L
AU  - Blomqvist, G
AU  - Greitz, T
AU  - Litton, J E
AU  - Bergström, M
AU  - Ehrin, E
AU  - Ericson, K
AU  - Eriksson, L
AU  - Ingvar, D H
AU  - Johansson, L
AU  - Nilsson, J L
AU  - Stone-Elander, S
AU  - Sedvall, G
AU  - Wiesel, F
AU  - Wiik, G
TI  - PET studies of glucose metabolism in patients with schizophrenia.
DP  - 1983 May 01
TA  - American Journal of Neuroradiology
PG  - 550--552
VI  - 4
IP  - 3
4099  - http://www.ajnr.org/content/4/3/550.short
4100  - http://www.ajnr.org/content/4/3/550.full
SO  - Am. J. Neuroradiol.1983 May 01; 4
AB  - The hypothesis of abnormal patterns of metabolism in schizophrenia was examined in a series of six young patients with psychotic symptoms satisfying the research diagnostic criteria. After intravenous injection of 11C-glucose obtained through a photosynthetic process, the regional activity of 11C in brain was measured with a four-ring positron camera. Regions of interest were obtained from computed tomographic images. Each patient underwent a second positron emission tomographic examinations after 4-5 weeks of treatment with a neuroleptic drug. No evidence of a hypofrontal pattern was found, but after treatment there was a reduced frontal uptake on the left side compared with temporal regions. The left-right asymmetry in the lentiform nucleus was reduced after treatment.