RT Journal Article SR Electronic T1 PET studies of glucose metabolism in patients with schizophrenia. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 550 OP 552 VO 4 IS 3 A1 Widen, L A1 Blomqvist, G A1 Greitz, T A1 Litton, J E A1 Bergström, M A1 Ehrin, E A1 Ericson, K A1 Eriksson, L A1 Ingvar, D H A1 Johansson, L A1 Nilsson, J L A1 Stone-Elander, S A1 Sedvall, G A1 Wiesel, F A1 Wiik, G YR 1983 UL http://www.ajnr.org/content/4/3/550.abstract AB The hypothesis of abnormal patterns of metabolism in schizophrenia was examined in a series of six young patients with psychotic symptoms satisfying the research diagnostic criteria. After intravenous injection of 11C-glucose obtained through a photosynthetic process, the regional activity of 11C in brain was measured with a four-ring positron camera. Regions of interest were obtained from computed tomographic images. Each patient underwent a second positron emission tomographic examinations after 4-5 weeks of treatment with a neuroleptic drug. No evidence of a hypofrontal pattern was found, but after treatment there was a reduced frontal uptake on the left side compared with temporal regions. The left-right asymmetry in the lentiform nucleus was reduced after treatment.