PT - JOURNAL ARTICLE AU - Maghnie, M AU - Genovese, E AU - Bernasconi, S AU - Binda, S AU - Aricò, M TI - Persistent high MR signal of the posterior pituitary gland in central diabetes insipidus. DP - 1997 Oct 01 TA - American Journal of Neuroradiology PG - 1749--1752 VI - 18 IP - 9 4099 - http://www.ajnr.org/content/18/9/1749.short 4100 - http://www.ajnr.org/content/18/9/1749.full SO - Am. J. Neuroradiol.1997 Oct 01; 18 AB - We describe three cases of central diabetes insipidus, each with a different pathogenesis, in which unexpected hyperintensity of the posterior pituitary gland was seen on T1-weighted MR images obtained at the time of presentation. In the first case (idiopathic), the posterior pituitary signal persisted more than 10 years; in the second case (Langerhans cell histiocytosis), the signal disappeared within 3 months, despite early specific chemotherapy with etoposide; and in the third case (transient), the posterior signal disappeared within 1 year, but it was documented at the time of spontaneous reversal of polyuria and polydipsia.