PT - JOURNAL ARTICLE AU - Whitehead, R E AU - Melhem, E R AU - Kasznica, J AU - Eustace, S TI - Telangiectatic osteosarcoma of the skull base. DP - 1998 Apr 01 TA - American Journal of Neuroradiology PG - 754--757 VI - 19 IP - 4 4099 - http://www.ajnr.org/content/19/4/754.short 4100 - http://www.ajnr.org/content/19/4/754.full SO - Am. J. Neuroradiol.1998 Apr 01; 19 AB - We present a patient with a distinctive lesion of the skull base, which, at imaging, showed expansile destruction of the sphenoid bone, hemorrhage with fluid-fluid levels, and contrast enhancement of a solid portion. These features ordinarily suggest either giant cell tumor or aneurysmal bone cyst; however, pathologic examination confirmed instead a rare variant of osteosarcoma of the telangiectatic type. Although imaging findings can indicate any of these possibilities, biopsy is an essential step in arriving at the diagnosis.