PT - JOURNAL ARTICLE AU - Pema, P J AU - Horak, H A AU - Wyatt, R H TI - Myelopathy caused by nitrous oxide toxicity. DP - 1998 May 01 TA - American Journal of Neuroradiology PG - 894--896 VI - 19 IP - 5 4099 - http://www.ajnr.org/content/19/5/894.short 4100 - http://www.ajnr.org/content/19/5/894.full SO - Am. J. Neuroradiol.1998 May 01; 19 AB - We describe a case of myeloneuropathy resulting from nitrous oxide abuse. MR imaging of the spine revealed symmetric abnormal signal in the posterior columns of the cervical cord. Myeloneuropathy is caused by inactivation of vitamin B12 by nitrous oxide. This syndrome can also be seen in patients with borderline vitamin B12 deficiency who have recently been anesthetized with nitrous oxide.