PT  - JOURNAL ARTICLE
AU  - Henson, J.W.
AU  - Ulmer, S.
AU  - Harris, G.J.
TI  - Brain Tumor Imaging in Clinical Trials
AID  - 10.3174/ajnr.A0963
DP  - 2008 Mar 01
TA  - American Journal of Neuroradiology
PG  - 419--424
VI  - 29
IP  - 3
4099  - http://www.ajnr.org/content/29/3/419.short
4100  - http://www.ajnr.org/content/29/3/419.full
SO  - Am. J. Neuroradiol.2008 Mar 01; 29
AB  - SUMMARY: There are substantial challenges in the radiologic evaluation of tumor size during clinical trials, and it is important for neuroradiologists to have a firm understanding of these issues. This review will examine measurement approaches, response criteria, selection of lesions for measurement, technical imaging considerations, interval between tumor measurements and response confirmation, and validity of imaging as a measure of efficacy.