RT Journal Article
SR Electronic
T1 Brain Tumor Imaging in Clinical Trials
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 419
OP 424
DO 10.3174/ajnr.A0963
VO 29
IS 3
A1 Henson, J.W.
A1 Ulmer, S.
A1 Harris, G.J.
YR 2008
UL http://www.ajnr.org/content/29/3/419.abstract
AB SUMMARY: There are substantial challenges in the radiologic evaluation of tumor size during clinical trials, and it is important for neuroradiologists to have a firm understanding of these issues. This review will examine measurement approaches, response criteria, selection of lesions for measurement, technical imaging considerations, interval between tumor measurements and response confirmation, and validity of imaging as a measure of efficacy.