PT - JOURNAL ARTICLE AU - Sundgren, P.C. TI - MR Spectroscopy in Radiation Injury AID - 10.3174/ajnr.A1580 DP - 2009 Sep 01 TA - American Journal of Neuroradiology PG - 1469--1476 VI - 30 IP - 8 4099 - http://www.ajnr.org/content/30/8/1469.short 4100 - http://www.ajnr.org/content/30/8/1469.full SO - Am. J. Neuroradiol.2009 Sep 01; 30 AB - SUMMARY: Detecting a new area of contrast enhancement in or in the vicinity of a previously treated brain tumor always causes concern for both the patient and the physician. The question that immediately arises is whether this new lesion is recurrent tumor or a treatment effect. The differentiation of recurrent tumor or progressive tumor from radiation injury after radiation therapy is often a radiologic dilemma regardless the technique used, CT or MR imaging. The purpose of this article was to review the utility of one of the newer MR imaging techniques, MR spectroscopy, to distinguish recurrent tumor from radiation necrosis or radiation injury.