RT Journal Article SR Electronic T1 Emergent Image-Guided Treatment of a Large CSF Leak to Reverse “In-Extremis” Signs of Intracranial Hypotension JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1627 OP 1629 DO 10.3174/ajnr.A1157 VO 29 IS 9 A1 Lasboo, A.A. A1 Hurley, M.C. A1 Walker, M.T. A1 Surdell, D. A1 Song, J.K. A1 Rosenow, J.M. A1 Shaibani, A. YR 2008 UL http://www.ajnr.org/content/29/9/1627.abstract AB SUMMARY: We report the use of an emergent, targeted fibrin spinal epidural blood patch with subarachnoid saline infusion to rapidly reverse “in-extremis” clinical and imaging signs of posterior-fossa coning brought about by acute-on-chronic intracranial hypotension, itself consequent to a cervicothoracic CSF leak. Treatment resulted in a dramatic recovery and eventual discharge with return to normal lifestyle and occupation. The clinical and imaging danger signs are reviewed; fibrin patch technique and potential pitfalls in postprocedure management are analyzed.