RT Journal Article
SR Electronic
T1 Outcome analysis of preoperative embolization with N-butyl cyanoacrylate in cerebral arteriovenous malformations.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1801
OP 1807
VO 16
IS 9
A1 DeMeritt, J S
A1 Pile-Spellman, J
A1 Mast, H
A1 Moohan, N
A1 Lu, D C
A1 Young, W L
A1 Hacein-Bey, L
A1 Mohr, J P
A1 Stein, B M
YR 1995
UL http://www.ajnr.org/content/16/9/1801.abstract
AB PURPOSE To determine the influence of preoperative N-butyl cyanoacrylate embolization on outcome in the treatment of cerebral arteriovenous malformations. METHODS Two groups were compared: 30 patients who underwent surgery and embolization versus 41 patients who underwent surgery only. Both groups were categorized by Spetzler-Martin grade and evaluated with the Glasgow Outcome Scale at various intervals. The long-term follow-up in months was, for surgery only, mean of 35 and range of 4 to 59, and for surgery and embolization, mean of 10 and range of 1 to 19). RESULTS The arteriovenous malformations in the surgery and embolization group had a larger average greatest diameter (4.2 +/- 1.5 cm versus 3.4 +/- 1.8 cm) and were of higher Spetzler-Martin grade (89% versus 68% grade III-V). No significant difference in the preoperative or immediate postoperative (less than 24 hours) Glasgow Outcome Scale was identified between the two groups. At I week after surgery, the surgery and embolization group displayed a significantly better outcome evaluation (70% versus 41% with Glasgow Outcome Scale score of 5). The long-term evaluation continued to favor the surgery and embolization patients (86% versus 66% with Glasgow Outcome Scale score of 5). CONCLUSION Preoperative N-butyl cyanoacrylate embolization improves postsurgical outcome.